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egfr agonist  (MedChemExpress)


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    MedChemExpress egfr agonist
    Egfr Agonist, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 25 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/egfr agonist/product/MedChemExpress
    Average 94 stars, based on 25 article reviews
    egfr agonist - by Bioz Stars, 2026-03
    94/100 stars

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    EGFR/EGFRvIII upregulated GLUT3 expression in glioblastoma. (A and B) EGFR and GLUT3 were substantially overexpressed in U87-EGFRvIII and LN229-EGFRvIII cells at the mRNA (A) and protein (B) levels compared with those in wild-type U87 and LN229 cells. (C) Through treatment of U87-EGFRvIII cells with osimertinib and NSC228115, we found that EGFR promoted the expression of GLUT3. Mean ± SD. ***P<0.001. P values were calculated using two-tailed Student’s t-tests and one-way ANOVA.

    Journal: American Journal of Translational Research

    Article Title: EGFR/EGFRvIII partly regulates the tumourigenesis of glioblastoma through the SOX9-GLUT3 axis

    doi:

    Figure Lengend Snippet: EGFR/EGFRvIII upregulated GLUT3 expression in glioblastoma. (A and B) EGFR and GLUT3 were substantially overexpressed in U87-EGFRvIII and LN229-EGFRvIII cells at the mRNA (A) and protein (B) levels compared with those in wild-type U87 and LN229 cells. (C) Through treatment of U87-EGFRvIII cells with osimertinib and NSC228115, we found that EGFR promoted the expression of GLUT3. Mean ± SD. ***P<0.001. P values were calculated using two-tailed Student’s t-tests and one-way ANOVA.

    Article Snippet: Additionally, after adding the EGFR agonist NSC228115 (HY-101084; MedChemExpress, 0.36 μM for 24 h) to U87-EGFRvIII cells, the expression of GLUT3 increased substantially, and after adding the EGFR inhibitor osimertinib (AZD-9291; MedChemExpress, 1 nM for 24 h) to U87-EGFRvIII cells, the expression of GLUT3 decreased substantially ( ).

    Techniques: Expressing, Two Tailed Test